The revolution involving the foundations of the physical sciences heralded by relativity and quantum theories has been stimulating philosophers for many years. Both of these comprehensive sets of concepts have involved profound challenges to traditional theories of epistemology, ontology, and language. This volume gathers six experts in physics, logic and philosophy to discuss developments in space exploration and nuclear science and their impact on the philosophy of science.

Seeking a scientific basis for understanding and treating mental illness, and inspired by the work of Ivan Pavlov, American physiologists, psychiatrists and psychologists in the 1920s turned to nonhuman animals. This paper examines how new constructs such as “experimental neurosis” emerged as tools to enable psychiatric comparison across species. From 1923 to 1962, the Cornell “Behavior Farm” was a leading interdisciplinary research center pioneering novel techniques to experimentally study nonhuman psychopathology. Led by the psychobiologist Howard Liddell, work at the Behavior (...) Farm formed part of an ambitious program to develop new preventative and therapeutic techniques and bring psychiatry into closer relations with physiology and medicine. At the heart of Liddell’s activities were a range of nonhuman animals, including pigs, sheep, goats and dogs, each serving as a proxy for human patients. We examine how Pavlov’s conceptualization of ‘experimental neurosis’ was used by Liddell to facilitate comparison across species and communication between researchers and clinicians. Our close reading of his experimental system demonstrates how unexpected animal behaviors and emotions were transformed into experimental virtues. However, to successfully translate such behaviors from the animal laboratory into the field of human psychopathology, Liddell increasingly reached beyond, and, in effect, redefined, the Pavlovian method to make it compatible and compliant with an ethological approach to the animal laboratory. We show how the resultant Behavior Farm served as a productive “hybrid” place, containing elements of experiment and observation, laboratory and field. It was through the building of close and more naturalistic relationships with animals over extended periods of time, both normal and pathological, and within and outside of the experimental space, that Liddell could understand, manage, and make useful the myriad behavioral complexities that emerged from the life histories of experimental animals, the researchers who worked with them, and their shared relationships to the wider physical and social environments. (shrink)

Natural selection is commonly interpreted as the fundamental mechanism of evolution. Questions about how selection theory can claim to be the all-sufficient explanation of evolution often go unanswered by today's neo-Darwinists, perhaps for fear that any criticism of the evolutionary paradigm will encourage creationists and proponents of intelligent design.In Biological Emergences, Robert Reid argues that natural selection is not the cause of evolution. He writes that the causes of variations, which he refers to as natural experiments, are independent of (...) natural selection; indeed, he suggests, natural selection may get in the way of evolution. Reid proposes an alternative theory to explain how emergent novelties are generated and under what conditions they can overcome the resistance of natural selection. He suggests that what causes innovative variation causes evolution, and that these phenomena are environmental as well as organismal.After an extended critique of selectionism, Reid constructs an emergence theory of evolution, first examining the evidence in three causal arenas of emergent evolution: symbiosis/association, evolutionary physiology/behavior, and developmental evolution. Based on this evidence of causation, he proposes some working hypotheses, examining mechanisms and processes common to all three arenas, and arrives at a theoretical framework that accounts for generative mechanisms and emergent qualities. Without selectionism, Reid argues, evolutionary innovation can more easily be integrated into a general thesis. Finally, Reid proposes a biological synthesis of rapid emergent evolutionary phases and the prolonged, dynamically stable, non-evolutionary phases imposed by natural selection. (shrink)

The 3Rs, or the replacement, reduction, and refinement of animal research, are widely accepted as the best approach to maximizing high-quality science while ensuring the highest standard of ethical consideration is applied in regulating the use of animals in scientific procedures. This contrasts with the muted scientific interest in the 3Rs when they were first proposed in The Principles of Humane Experimental Technique. Indeed, the relative success of the 3Rs has done little to encourage engagement with their original text, which (...) remains little read and out of print. By adopting a historical perspective, this article argues that one explanation for this disjunction may be found in another, more celebrated, event of 1959: C. P. Snow’s Rede lecture on The Two Cultures. The moral outlook of The Principles of Humane Experimental Technique derived from an earlier ethos wherein humanistic and scientific values occupied a shared culture. While the synthetic style of The Principles has hindered its readership, this article concludes that there is value to recovering the notion that the humanities and social sciences can contribute to the improvement of animal research. (shrink)

The principles of the 3Rs—replacement, refinement, and reduction—strongly shape discussion of methods for performing more humane animal research and the regulation of this contested area of technoscience. This special issue looks back to the origins of the 3Rs principles through five papers that explore how it is enacted and challenged in practice and that develop critical considerations about its future. Three themes connect the papers in this special issue. These are the multiplicity of roles enacted by those who use and (...) care for animals in research, the distribution of “feelings that matter” across species and spaces of laboratory animal practice, and the growing importance of “cultures of care” in animal research. (shrink)

ABSTRACT:Neuroethics, the study of the cognitive and neural mechanisms underlying ethical decision-making, is a growing field of study. In this review, we identify and discuss four themes emerging from neuroethics research. First, ethical decision-making appears to be distinct from other types of decision-making processes. Second, ethical decision-making entails more than just conscious reasoning. Third, emotion plays a critical role in ethical decision-making, at least under certain circumstances. Lastly, normative approaches to morality have distinct, underlying neural mechanisms. On the basis of (...) these themes, we draw implications for research in business ethics and the practice of ethics training. (shrink)

Chemistry laboratories, as buildings, have been surprisingly little studied by historians of science; interest has been focused on them more as sites of specific scientific activity, with particular emphasis on the personalities who worked within them. This has overshadowed aspects of laboratories such as their specification, design, construction, fitting-out, adaptation, replacement, status as civic and academic structures, and so on. Systematic study of them would be aided by an agreed taxonomy of laboratory types, according to their purpose, and a scheme (...) is proposed here. Practically no pre-1800 chemical laboratories survive, and there are very few dating from earlier than 1900, at least in their original state. Encouragingly, there have been several recent archaeological excavations which have turned up interesting evidence of early examples from various cultures. Little interest has been shown in the preservation of laboratories as significant architectural or historical structures, certainly when compared with other building types. The paper closes by considering those English laboratories which enjoy some level of legal protection but questioning the criteria adopted in deciding the programme of preservation. (shrink)

THIS PAPER ARGUES, AGAINST A. O. LOVEJOY AND WITH R. B.\nPERRY, THAT JAMES' THEORY OF MEANING DOES NOT CONFUSE\nCONSEQUENCES OF BELIEVING AND CONSEQUENCES OF THE\nSTATEMENTS BELIEVED. RATHER, I ARGUE THAT JAMES HOLDS THAT\nTHE MEANING OF A SYNTHETIC STATEMENT IS TO BE FOUND IN ITS\nPERCEPTUAL CONSEQUENCES WHILE CONSEQUENCES OF BELIEVING ARE\nRELEVANT TO 'JUSTIFYING' OVERBELIEFS; THAT IS, TO\nJUSTIFYING MEANINGFUL STATEMENTS FOR WHICH THE EVIDENCE IS\nINSUFFICIENT TO PROVIDE A RATIONAL, NON-PASSIONAL\nJUSTIFICATION. ALTHOUGH THIS THEORY OF MEANING APPEARS\nANTI-METAPHYSICAL, JAMES DOES NOT USE IT TO RULE (...) OUT\nMETAPHYSICS BECAUSE HE BELIEVES, ALONG WITH COMMON SENSE,\nTHAT METAPHYSICAL DOCTRINES ARE MEANINGFUL; THUS, THE\nQUESTION IS WHAT METAPHYSICAL DOCTRINES MEAN AND NOT\nWHETHER THEY ARE MEANINGFUL. ALTHOUGH JAMES IS OFTEN\nMISLEADING IN TALKING ABOUT MEANING, I ARGUE THAT THIS\nINTERPRETATION IS SUPPORTED BY HIS NUMEROUS DISCUSSIONS OF\nMETAPHYSICS. PAUL HENLE'S ATTEMPT TO PROVIDE A FAVORABLE\nINTERPRETATION OF JAMES WITHIN LOVEJOY'S FRAMEWORK, IS ALSO\nSHOWN TO BE INCOHERENT. (shrink)

Appropriate enablers are essential for management of intellectual capital. Through the use of structural equation modeling, we investigate whether organic renewal environments, interactive behaviors, and trust are conducive to intellectual capital management processes, as they each depend upon the establishment of a climate emphasizing mutual respect. Owing to a lack of clarity in the literature, we tested the ordering of the variables and found statistical significance for two ordering alternatives. However, the sequence presented in this article provides the best statistical (...) fit: an organic renewal environment provides a foundation for interactive behaviors, which leads to trust, and thus is consistent with the development of intellectual capital management pro- cesses within the organization. (shrink)

Focuses primarily on those works of classical and modern philosophy, psychology and theology that have dealt with man -- with human love. Exploring the writing of authors as diverse as Aristotle, Dante, Sigmund Freud, Descartes and David Hume, the author attempts in each case to isolate the basic notion or notions that are common to all the forms of interpersonal love: the elements he implies must be present in love, and those he suggests may, in addition, be present to distinguish (...) one type of love from another. (shrink)

The goal of this paper is to defend the claim that there is such a thing as direct perception, where by ‘direct perception’ I mean perception unmediated by theorizing or concepts. The basis for my defense is a general philosophic perspective which I call ‘empiricist philosophy’. In brief, empiricist philosophy (as I have defined it) is untenable without the occurrence of direct perception. It is untenable without direct perception because, otherwise, one can't escape the hermeneutic circle, as this phrase is (...) used in van Fraassen (1980). The bulk of the paper is devoted to defending my belief in direct perception against various objections that can be posed against it. I discuss various anticipations of my view found in the literature, eventually focusing on Ian Hacking's related conception of `entity realism' (Hacking 1983). Hacking has been criticized by a number of philosophers and my plan is to respond to these criticisms on behalf of entity realism (or more precisely on behalf of the claim that direct perception is a reality) and to then respond to other possible criticisms that can be launched against direct perception. (shrink)

The WIMP (weakly interacting dark matter) is currently the leading candidate for what is thought to be dark matter, the cosmological material claimed to make up almost 99% of the matter of the universe and which is indiscernible by means of electromagnetic radiation. There are many research groups dedicated to experimentally isolating WIMPs, and in this paper we describe the work of three of these groups, the Saclay group, DAMA and UKDM. This exploration into the recent history of astroparticle physics (...) serves to illuminate two philosophical issues. First, is confirmatory evidence more compelling if it coordinates results gleaned from independent experimental investigations? And secondly, in justifying experimental conclusions, how strong must this justification be? Are the high standards set by philosophers, in the spirit of Descartes, relevant to experimental research? (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Eidos/idea in IsocratesRobert G. SullivanFor modern readers, the career and literary output of the Attic rhetorician Isocrates is uncomfortably situated at the boundary between what we conceive as technical rhetoric and professional philosophy. Much of this confusion may be due to Isocrates' famous description of his program as being a philosophia (Panegyricus 10, 47; Evagoras 8, 81; Panathenaicus 9; Against the Sophists 1, 11-18, 21; Antidosis 30, 42-50, 162, (...) 176, 181-92).1 Over the years, the issue has exercised a large number of scholars who have tried to specify what Isocrates meant by the term and what matters he considered to be within his purview.2 Recently, the idea has been advanced that Isocrates and Plato consciously struggled over the use of the term (Nehamas 1990, 4; Timmerman 1998, 145). In Nehamas's very useful formulation, Isocrates thought philosophy to be "the ability to speak well, which in turn reflects and is the product of thinking well and shrewdly about practical affairs" (1990, 4). Timmerman's review of the relevant literature shows how Isocrates' conflation of philosophia and hê tôn logôn paideia has hurt his reputation among modern disciplinary philosophers: "This confusion and resultant devaluation of Isocrates' philosophy is predicated on a platonically colored view of what constitutes philosophy" (1998, 147). More recently, others have made efforts to recover Isocrates for philosophy by concentrating on those parts of his program that are of interest to philosophers of our era.3As a result, there has been a long-standing critical misapprehension regarding how best to interpret his works. Simply put, a question arises as to whether we should interpret them as bei. (shrink)

In 1912, Henri Poincaré published an argument which apparently shows that the hypothesis of quanta is both necessary and sufficient for the truth of Planck''s experimentally corroborated law describing the spectral distribution of radiant energy in a black body. In a recent paper, John Norton has reaffirmed the authority of Poincarés argument, setting it up as a paradigm case in which empirical data can be used to definitively rule out theoretical competitors to a given theoretical hypothesis. My goal is to (...) dispute Norton ''s claim that there is no theoretical underdetermination problem arising between classical physics and early quantum theory. The strategy I use in defending my view is to adopt a suggestion made by Jarrett Leplin and Larry Laudan on how to assess the relative merits of competing theoretical alternatives, where each alternative has an equal capacity to save the phenomena. In the course of the paper, I distinguish between two branches of classical physics: classical mechanics and classical electromagnetism. The former is claimed by Norton and Poincaré to be determinately ruled out by the black body evidence; and it is the former that I argue is compatible with this evidence. (shrink)

Freud attributed uncovered incest, initially, to real abuse dissociated from self-consciousness, and later, to wishes repressed from consciousness. Dissociation is preferred on theoretical and empirical grounds. Whereas dissociation emerges from double-aspect materialism, repression implicates Cartesian dualism. Several studies suggest that abnormal individuals dissociate trauma from self-conscious source-monitoring, thereby convincing themselves that the trauma is imaginary rather than real, and re-experience the trauma as an unbidden image.

How do thought and language manage to be 'about' aspects of the world? J. Robert G. Williams investigates how representation arises out of a fundamentally non-representational world, showing the explanatory relations between the representational properties of language, of thought, and of perception and intention.

Culp (1994) provides a defense for a form of experimental reasoning entitled 'robustness'. Her strategy is to examine a recent episode in experimental microbiology--the case of the mistaken discovery of a bacterial organelle called a 'mesosome'--with an eye to showing how experimenters effectively used robust experimental reasoning (or could have used robust reasoning) to refute the existence of the mesosome. My plan is to criticize Culp's assessment of the mesosome episode and to cast doubt on the epistemic significance of robustness. (...) In turn, I present a different account of the experimental reasoning microbiologists used in arriving at the conclusion that mesosomes are artifacts. I call this form of reasoning 'reliable process reasoning', and close the paper with a brief discussion of how experimental microbiologists justify the claim that an experimental process is reliable. (shrink)

It is claimed that 'Do x!' means 'Then you will do x'. Answering a "Why?" question concerning the former may take either of two forms, viz., 'Because --' or 'If you wish to --'. The second answer completes the truncated hypothetical. "Ought" sentences are treated as a species of imperatives involving universality in the "if" clause ('If anyone wished to --'). Moral "ought" sentences involve a double universality, viz., the one mentioned above and universality connecting the action with social harmony (...) (e.g., "If everyone were to do x, then there would be social harmony'). (shrink)